Jennifer Weuve

a research and faculty member profile

Alzheimer disease in individual US states and DC: now and in the future

Weuve J, Hebert LE, Scherr PA, Evans DA. Prevalence of Alzheimer disease in individual US states and the District of Columbia, 2010-2025 [research letter]. Epidemiology (in press).

Dietary pattern and risk of Alzheimer disease.

A summary of epidemiologic studies of dietary pattern and risk of Alzheimer disease dementia.  Credits: Koyama A, Weuve J, Jackson JW, Blacker D.

Exposure to lead appears to increase homocysteine. Could diet blunt the impact?

Bakulski KM, Park, SK, Weisskopf MG, Tucker KL, Sparrow D, Spiro III A, Vokonas PS, Nie LH, Hu H, Weuve J. Lead exposure, B-vitamins, and plasma homocysteine in older men. Environmental Health Perspectives. Published online June 6, 2014.

(Source: ehp.niehs.nih.gov)

Two great disciplines that go great together: air pollution and dementia epidemiology.

Weuve J. Invited commentary: what exposure to air pollutants may be doing to the aging brain and what epidemiology can say about it. American Journal of Epidemiology. Published online June 24, 2014.

(Source: ncbi.nlm.nih.gov)

Exposure to lead and changes in cognitive function.

Power MC, Korrick S, Tchetgen Tchetgen EJ, Nie LH, Grodstein F, Hu H, Weuve J, Schwartz J, Weisskopf MG. Lead exposure and rate of change in cognitive function in older women. Environmental Research 2014;129:69-75.

(Source: ncbi.nlm.nih.gov)

How many people in the U.S. have Alzheimer disease when they die?

Weuve J, Hebert LE, Scherr PA, Evans DA. Deaths in the United States among persons with Alzheimer’s disease dementia (2010-2050). Alzheimer’s & Dementia 2014;10:e40-e46.

(Source: sciencedirect.com)

Exposure to PCBs in association with cognition in older age.

Bouchard MF, Oulhote Y, Sagiv SK, Saint-Amour D, Weuve J. Exposure to polychlorinated biphenyls and cognition in older US adults: NHANES (1999-2002). Environmental Health Perspectives 2014 Jan;122(1):73-78.

Related story

Dangers of PCBs still lurking (The Montreal Gazette)

(Source: ncbi.nlm.nih.gov)

Postmenopausal hormone therapy and dementia: unexpected meta-analytical findings.

O’Brien J, Jackson JW, Grodstein F, Blacker D*, Weuve J*.  Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer’s disease: a new systematic review and meta-analysis of prospective observational and trial data. Epidemiologic Reviews 2014;36(1):83-103.  *contributed equally.

See the complementary entry on AlzRisk here.

(Source: epirev.oxfordjournals.org)

Legacy of lead exposure on cognition in the aging brain: a review.

Weuve J, Weisskopf MG. Chapter 1: Cognitive dysfunction and lead. In: Aging and Vulnerability to Environmental Chemicals. Weiss B, ed. Cambridge, UK: Royal Society of Chemistry, 2013: pp 5-30; doi: 10.1039/9781849734660-00005.

(Source: pubs.rsc.org)

Alzheimer disease in the U.S.: now through 2050.

Hebert LE, Weuve J, Scherr PA, Evans DA. Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Neurology 2013 May 7;80(19):1778-1783.

Selected related stories

Alzheimer’s rates expected to triple by 2050 because of aging baby boomers (CBS News)

Number of Americans With Alzheimer’s May Triple by 2050 (HealthDay)

An Alzheimer’s ‘epidemic’ could hit the USA by 2050 (USA TODAY)

(Source: neurology.org)

The red blood cell distribution width and prevalent dementia.

Weuve J, Mendes de Leon CF, Bennett DA, Dong X, Evans DA. The red cell distribution width and anemia in relation to prevalent dementia. Alzheimer Disease & Associated Disorders 2014 Apr-Jun;28(2):99-105.

(Source: ncbi.nlm.nih.gov)

Cumulative lead exposure and cognition in persons with Parkinson’s disease.

Weuve J, Press DZ, Grodstein F, Wright RO, Hu H, Weisskopf MG. Cumulative exposure to lead and cognitive function in persons with Parkinson’s disease. Movement Disorders 2013 Feb;28(2):176-182.

(Source: ncbi.nlm.nih.gov)

Diabetes and Alzheimer disease.

A summary and meta-analysis of epidemiologic studies of diabetes, glucose and insulin measures in relation to Alzheimer disease.  Credits:  Sajeev G*, Weuve J*, McQueen MB, Blacker D.
* contributed equally.

Inflammatory markers in blood in relation to dementia risk.

Koyama A, O’Brien J, Weuve J, Blacker D, Metti AL, Yaffe K. The role of peripheral inflammatory markers in dementia and Alzheimer’s disease: a meta-analysis. J Gerontol A Biol Sci Med Sci 2013 Apr;68(4):433-440.

(Source: ncbi.nlm.nih.gov)