Jennifer Weuve

a research and faculty member profile

Exposure to lead and changes in cognitive function.

Power MC, Korrick S, Tchetgen Tchetgen EJ, Nie LH, Grodstein F, Hu H, Weuve J, Schwartz J, Weisskopf MG. Lead exposure and rate of change in cognitive function in older women. Environmental Research 2014;129:69-75.

(Source: ncbi.nlm.nih.gov)

How many people in the U.S. have Alzheimer disease when they die?

Weuve J, Hebert LE, Scherr PA, Evans DA. Deaths in the United States among persons with Alzheimer’s disease dementia (2010-2050). Alzheimer’s & Dementia 2014;10:e40-e46.

(Source: sciencedirect.com)

Exposure to PCBs in association with cognition in older age.

Bouchard MF, Oulhote Y, Sagiv SK, Saint-Amour D, Weuve J. Exposure to polychlorinated biphenyls and cognition in older US adults: NHANES (1999-2002). Environmental Health Perspectives 2014;2014 Jan;122(1):73-78.

Related story

Dangers of PCBs still lurking (The Montreal Gazette)

(Source: ncbi.nlm.nih.gov)

Exposure to lead appears to increase homocysteine. Could diet blunt the impact?

Bakulski KM, Park, SK, Weisskopf MG, Tucker KL, Sparrow D, Spiro III A, Vokonas PS, Nie LH, Hu H, Weuve J. Lead exposure, B-vitamins, and plasma homocysteine in older men. Environmental Health Perspectives (in press). 

Postmenopausal hormone therapy and dementia: unexpected meta-analytical findings.

O’Brien J, Jackson JW, Grodstein F, Blacker D*, Weuve J*.  Postmenopausal hormone therapy is not associated with risk of all-cause dementia and Alzheimer’s disease: a new systematic review and meta-analysis of prospective observational and trial data. Epidemiologic Reviews 2014;36(1):83-103.  *contributed equally.

(Source: epirev.oxfordjournals.org)

Legacy of lead exposure on cognition in the aging brain: a review.

Weuve J, Weisskopf MG. Chapter 1: Cognitive dysfunction and lead. In: Aging and Vulnerability to Environmental Chemicals. Weiss B, ed. Cambridge, UK: Royal Society of Chemistry, 2013: pp 5-30; doi: 10.1039/9781849734660-00005.

(Source: pubs.rsc.org)

Alzheimer disease in the U.S.: now through 2050.

Hebert LE, Weuve J, Scherr PA, Evans DA. Alzheimer disease in the United States (2010–2050) estimated using the 2010 census. Neurology 2013 May 7;80(19):1778-1783.

Selected related stories

Alzheimer’s rates expected to triple by 2050 because of aging baby boomers (CBS News)

Number of Americans With Alzheimer’s May Triple by 2050 (HealthDay)

An Alzheimer’s ‘epidemic’ could hit the USA by 2050 (USA TODAY)

(Source: neurology.org)

The red blood cell distribution width and prevalent dementia.

Weuve J, Mendes de Leon CF, Bennett DA, Dong X, Evans DA. The red cell distribution width and anemia in relation to prevalent dementia. Alzheimer Disease & Associated Disorders (in press).

(Source: ncbi.nlm.nih.gov)

Cumulative lead exposure and cognition in persons with Parkinson’s disease.

Weuve J, Press DZ, Grodstein F, Wright RO, Hu H, Weisskopf MG. Cumulative exposure to lead and cognitive function in persons with Parkinson’s disease. Movement Disorders 2013 Feb;28(2):176-182.

(Source: ncbi.nlm.nih.gov)

Inflammatory markers in blood in relation to dementia risk.

Koyama A, O’Brien J, Weuve J, Blacker D, Metti AL, Yaffe K. The role of peripheral inflammatory markers in dementia and Alzheimer’s disease: a meta-analysis. J Gerontol A Biol Sci Med Sci 2013 Apr;68(4):433-440.

(Source: ncbi.nlm.nih.gov)

Socioeconomic inequalities in health: do our methods do them justice?

Weuve J. Magnitude matters: beyond detection in the presence of selection, in research on socioeconomic inequalities in health [invited commentary]. Epidemiology 2013 Jan;24(1):10-13.

(Source: ncbi.nlm.nih.gov)

Polycyclic aromatic hydrocarbons, PM air pollution, and cognitive decline.

Weuve J, Yanosky JD. Polycyclic aromatic hydrocarbons, particulate air pollution, and cognitive decline-reply. Archives of Internal Medicine 2012 Jul 9;172(13):1045-1046.

In reply to letter about study of PM exposure and cognitive decline.

Exposure to lead in relation to depressive and anxiety symptoms.

Eum K-D, Korrick SA, Weuve J, Okereke O, Kubzansky LD, Hu H, Weisskopf MGRelation of cumulative low-level lead exposure to depressive and phobic anxiety symptom scores in middle-aged and elderly women. Environmental Health Perspectives 2012;160(6):817-823.

Related story (Environmental Health News)

(Source: ncbi.nlm.nih.gov)

Exposure to particulate air pollution and cognitive decline.

Weuve J, Puett RC, Schwartz J, Yanosky JD, Laden F*, Grodstein F*. Exposure to particulate air pollution and cognitive decline in older women. Archives of Internal Medicine 2012;172(3):219-227.

* contributed equally.

Selected related stories:

Invited commentary (Archives of Internal Medicine)

Letter to the editor and reply (Archives of Internal Medicine)

Smog in our brains (Monitor on Psychology, American Psychological Association)

Common air pollutant linked to mental decline (WBEZ, Chicago Public Radio)

Pollution can put minds in a fog (Chicago Tribune)

Smog may harm women’s brains (HealthDay via MSN)

Air pollution tied to heart and brain risks (Well of the New York Times)

Air pollution ups risk of stroke, impaired memory (Science Friday)

Air pollution linked to cognitive decline (Voice of America)

Correlation structure in inverse-probability-weighted analyses of repeated measures: a cautionary note.

Tchetgen ET, Glymour MM, Weuve J, Robins JM. Specifying the correlation structure in inverse-probability-weighting estimation for repeated measures. Epidemiology 2012 Jul;23(4):644-6.

Clarification on the methods used in this paper on using inverse probability of attrition weights to account for selective attrition.

(Source: journals.lww.com)